Reds give debuts to Dawit Szczepaniak, Max Cleworth and Jake Bickerstaff, while the youth team make up the rest of the bench.
Wrexham: Szczepaniak (g/k), Lawlor, Tharme, Cleworth, Barnum-Bobb, Redmond, Barton, Tollitt, Rutherford, McIntosh, Bickerstaff.
Subs: Dibble (g/k), Williams, Beaumont, Huxley, Jones, Parry, Robinson-Murray.
Ayr United: Hare-Reid (g/k), Muirhead, Kerr, Roscoe, Geggan, Moffat Dooland, Forrest, McCowan, Bell, Docherty.
Subs: Graham (g/k), Ecrepont, McKenzie.
Referee: Steven Gregg (N Ireland)