There is a debut for Callum Preston, after an injury to Christian Dibble, while Kevin Roberts and Scott Boden return to the starting line-up.
On the bench, scholar Doug Tharme is named amongst the substitutes.
Wrexham: Preston, Carrington, M Smith, Pearson, Roberts, Rutherford, Wright, Wedgbury, L Smith, Boden, Reid.
Subs: Tharme, Marx, Mackreth, Holroyd, Massanka.
Hartlepool United: Loach, Magnay, Wtason, Ledger, Deverdics, Featherstone, Woods, Hawkins, Franks, Oates, Rodney
Subs: Laing, Newton, Donnelly, Donaldson, Munns
Referee: Joe Johnson (Merseyside)